New Product & Service Updates

Fc-Engineered Antibody Expression Vectors

Published November 23, 2023

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c-Engineered Antibody Expression Vectors with enhanced Fc-effector function are now available in store. These include human IgG1 and IgG4 heavy chains with increased or decreased ADCC and CDC, an aglycosylated human IgG1 heavy chain variant, and a human IgG1 with extended serum half-life.

New Phagemid Vectors

Published August 13, 2023

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hagemid vectors pADL-43 and pADL-23Chlo are now available in store. The pADL-23Chlo™ phagemid is a variant of pADL-23c™ that uses a different antibiotic marker. pADL™-43 allows display on a truncated version of pIII, similarly to pComb3 vector. Both vectors completes the series of phagemids offered by Antibody Design Labs.

MIM™ Peptide Phage Libraries

Published January 16, 2023


The MIM™ Phage Display Peptide Libraries are full-phage libraries consisting of ~109 random peptides displayed as an N-terminal fusion protein with the minor coat protein pIII. These libraries are similar to the libraries originally developed by George Smith and are currently available as a 12-mer (NH2-X12GGGSGPGGLRGGS-pIII, MIM-12) and cyclic 10-mer (NH2-AEGCX10C GGGSGPGGLRGGS-pIII, MIM-C10) phage libraries. A lysine conveniently located in the linker allows for the more efficient trypsin elution.

Novel Mammalian Expression Vector Series

Published January 10, 2023

The TGEX™ Vector Series is getting an upgrade! The new series has been optimized for improved expression of recombinant antibodies and now offers the selection of stable pools and stable transformants using antibiotics. The series offers a complete coverage of human, mouse and rabbit IgG isotypes as well as several vectors for the expression of Fab fragments and Fc fusions.

fADL-2blue: A Trypsin-Sensitive Helper Phage Vector

Published October 04, 2021
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hage vector fADL-2blue is now available in store. The fADL-2blue™ phage vector continues the fADL phage vector series by bringing trypsin-sensitivity for elution together with ampicillin-resistance and blue colonies that together limit contaminations by other phage. fADL-2blue also has an improved virion production and a higher content of DNA in its replicative form. fADL-2blue™ rivals with the best vectors build by George Smith, the inventor of phage display.

High Specificity anti-M13 g8p Antibody

Published October 05, 2020

This new anti-M13 g8p antibody is one of the highest sensitivity M13 antibody on the market. With a detection threshold as low as 10^7-10^8 cfu/ml by phage ELISA, no more lost clones or binders that come and go! This new antibody is a must-have and essential component of your phage toolbox.

CM13d3 pIII-Defective Helper Phage

Published May 03, 2019


CM13d3 is a novel helper phage engineered for multivalent phage display. CM13d3 lacks a functional gene III driving the display of pIII-fusion proteins expressed by the phagemid. CM13d3 is similar to pIII-defective helpers such as M13KO7d3, Hyperphage, Ex-Phage or Phaberge that have been shown to increase display of scFv by a factor up to 100-fold and more. CM13d3 is highly infective, making it de facto the best choice for building libraries.

ALTHEA Gold Libraries

Published January 05, 2019

San Diego, December 2018: ADL presents the ALTHEA Gold Libraries™ at the Antibody Engineering and Therapeutics conference. These are very large semisynthetic single-chain Fv (scFv) libraries enriched in stable and developable antibodies for therapeutic applications.

Universal Phage Display System

Published November 17, 2017

The Universal Phage Display System (pUP System) enables the single step cloning of highly diverse Fab libraries with a large coverage of the immune response. This novel cloning system is available as a service for the construction of Fab Libraries.

  1. Nelson, R.S., & Valadon, P. (2017). A universal phage display system for the seamless construction of Fab libraries. J Immunol Methods, 450, 41-49.

Fluorescent GFP Reporter for Transfection Efficiency

Published September 11, 2017

The TGEX™-eGFP vector is a green fluorescent reporter designed to monitor transfection efficiency during transient gene expression in mammalian cell suspensions culture. TGEX™-eGFP vector can be used as a single component during transfection to analyze transfection efficiency or at a lower level, between 5% and 10% of the total DNA, to measure efficiency during transient gene expression.